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Qualaquin is prescribed to treat malaria, a disease commonly caused by mosquito bites. Malaria is common in areas such as Africa, South America and southern Asia. Although the FDA has warned against this use, Qualaquin has been prescribed to treat nighttime leg cramps or restless leg syndrome (RLS) as well. In 2006, the FDA banned all forms of the drug except for Qualaquin, the brand name for quinine.
Off-label uses of this drug have been studied and the FDA has found that side effects that could occur from taking Qualaquin are much riskier than the disorders they have been used to treat (ex. RLS). Qualaquin has been linked to several dangerous drug disorders such as thrombocytopenia and hemolytic uremic syndrome. These disorders can cause severe bleeding or irreversible kidney damage. Between 2005 and 2008, there were 38 reports of negative reactions to Qualaquin—18 cases required hospitalization and two patients died from complications related to the drug. Of these patients, only one of them was taking Qualaquin for the intended use of treating malaria.
Serious side effects may include:
Less serious side effects may include:
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