Valproate Sodium (Injection)

Valproate sodium is injected in order to control seizures related to epilepsy. This medication can also be used to help control the manic phase of severe bipolar disorder and to treat migraine headaches, although it cannot be used to prevent the onset of migraines. This medication increases the amount of certain brain chemicals to prevent seizures and other brain problems.

Side Effects/Warnings

This medication can cause liver failure. Liver damage usually occurs during the first six months of treatment, though it can occur at any point. Children under the age of 2 are at greater risk for fatal liver disease while on this medication than the general population. Contact your doctor immediately if you or your child has the following symptoms while on this medication:

  • Lethargy
  • Loss of appetite
  • Nausea and vomiting
  • Severe stomach pain
  • Brown urine
  • Tarry black stools
  • Jaundice

Do not take this medication while pregnant. It causes spina bifida and other severe birth defects.

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