Estradiol and Drospirenone are used to help reduce symptoms of menopause as well as to prevent unwanted pregnancies. These medications increase the amount of estrogen in the body. Women who suffer from poly-cystic ovary syndrome or other diseases that cause them to have difficulties when menstruating may also take this medication to regulate periods and reduce cramping, bloating and mood swings associated with PMS.
Women who take these medications should not smoke. Smoking increases the risk of heart attack or stroke while on estrogen. Heavy smokers are at greater risk than light smokers, but the safest choice is to abstain from smoking altogether. Women over the age of 35 are at even greater risk of heart attack or stroke if they smoke while on this medication than younger women.
This medication can also cause breast cancer and endometrial cancer, so patients should get regular cancer screenings.