Patients who receive a large number of blood transfusions may develop a problem in which they have too much iron in their blood. Deferasirox is an iron chelator; this medication works by pulling iron out of the bloodstream so that it is excreted when the patient uses the bathroom.

Warnings/Side Effects

Patients who suffer from liver or kidney disease should not take this medication. Deferasirox makes it more likely that a patient will have a liver or kidney problem. Patients should contact their doctors right away if they have any of the following problems:

  • Extreme fatigue
  • Severe pain in the stomach or lower back
  • Changes in urination frequency or difficulty urinating
  • Black, tarry stools or brown urine
  • Jaundice

Patients should also refrain from taking aspirin or other blood-thinning medications with Deferasirox in order to reduce the risk of excessive bleeding or internal bleeding in the stomach or intestines.

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